Friday, July 5, 2024

HIV: A Lethal Scourge Of The 1980s-1990s... More Or Less... Banished -- To The Dustbins Of BioScience History?


There is almost no way to fully-convey what a dramatic turnaround this represents, here nearly 40 years later.

The AIDS crisis meant that if diagnosed, it was mostly only a question of how soon you'd succumb, not whether you might recover. It was rightly considered exceedingly lethal, and always resulted in a heinously torturous. . . end. [Almost everyone I knew back then. . . knew someone who'd suffered and died of the disease -- many at someone else's bed-side -- helplessly watching it happen.]

Fast forward at least thirty years. It seems today, that the largest part of these excellent jab results are the product of drug compliance. The daily pill versions are highly effective, but only if they are religiously taken. . . every day. [So real world results fall to around 30% effectiveness, when multiple doses are missed.]

The use of twice a year injections, on the other hand. . . largely takes forgetfulness out of the equation, so it is fair to call this a "cure" now. As ever, getting it to a price point that most might afford. . . will be the real challenge from here:

. . .Gilead Sciences Inc.’s experimental twice-yearly shot prevented 100% of HIV cases in women and adolescent girls in Africa, the first successful big trial of what’s hoped to become a powerful new drug regimen for fending off the virus. . . .


As ever -- progress. . . progress in bio-science is grin-inducing, for me -- personally. Onward!

नमस्ते

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