Thursday, May 30, 2024

Back To Power Alley: No More Need For Dentures, Circa... 2030?


Clinical trials will begin in about six weeks, in Japan.

The idea that the body can regenerate its own new teeth has long been known, but the side effects were considered unacceptable. It seems the Japanese scientists have solved that issue. We will keep a close eye on this one:

. . .The world's first human trial of a drug that can regenerate teeth will begin in a few months, less than a year on from news of its success in animals. This paves the way for the medicine to be commercially available as early as 2030.

The trial, which will take place at Kyoto University Hospital from September to August 2025, will treat 30 males aged 30-64 who are missing at least one molar. The intravenous treatment will be tested for its efficacy on human dentition, after it successfully grew new teeth in ferret and mouse models with no significant side effects.

"We want to do something to help those who are suffering from tooth loss or absence," said lead researcher Katsu Takahashi, head of dentistry and oral surgery at Kitano Hospital. "While there has been no treatment to date providing a permanent cure, we feel that people's expectations for tooth growth are high. . . ."

Molecular biologist and dentist Takahashi has been working on tooth regeneration since 2005, and hopes this treatment won't just be for congenital dental conditions but for anyone who has lost teeth, at any age. . . .


Onward, flashing a toothy grin, tonight -- for a host of reasons. . . what a time to be. . . alive!

नमस्ते

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