Showing posts with label Jardiance Lilly Arrives Competition Booms Isentress May 1 2013 Januvia Entering Q1 2013 India Patent Glenmark Pharma Sitagliptin Generic June 25 2013 August 24 September 17 2015. Show all posts
Showing posts with label Jardiance Lilly Arrives Competition Booms Isentress May 1 2013 Januvia Entering Q1 2013 India Patent Glenmark Pharma Sitagliptin Generic June 25 2013 August 24 September 17 2015. Show all posts

Thursday, September 17, 2015

As We Previously Predicted, Lilly's SGLT-2 Will Get A Boost, Even As Merck Hits Headwinds -- In Diabetes


Even as Merck was outlining its pipeline, and plans, at the Morgan Stanley confab -- in the diabetes management franchise -- it was actually Lilly's new SGLT-2 drug making the real waves today in that space.

Just as we had directly suggested in August, the cardio-protective side benefit of Lilly's Jardiance® may well cause a sea-change, among prescribers -- away from Kenilworth's Januvia®. Here is a bit of the Reuters item, of earlier today:

. . . .Sanford Bernstein analyst Tim Anderson more than tripled his annual sales forecast for Jardiance and combination drugs containing it to $2.7 billion by 2020. He cut his 2020 sales forecast for Merck & Co Inc's Januvia, the leading member of a competing class of oral diabetes drugs called DPP-4 inhibitors, to $6 billion from $7.8 billion.

Anderson estimates Jardiance could boost Lilly's earnings per share by 8 percent on average across 2016 to 2020.

In the study, patients taking Jardiance had a 38 percent reduction in cardiovascular death, including from heart attacks and strokes. There was no significant difference in non-fatal heart attacks or non-fatal strokes. . . .


To be sure, Merck will be fine -- with Keytruda® (in cancers) off and running, and more than filling the Januvia revenue gap, in years beyond 2016. But in the short term, it may prove to be a bit of a pinch -- at the revenue line, globally. Hooray -- it is almost Friday!