Wednesday, June 18, 2014

After Last Month's European Oncology Filing Withdrawal, Vintafolide Returned To Endocyte


No surprise -- after the disappointing cancer study (non-survival results) surfaced, last month.

Here is the bit from The Pharma Letter, overnight:

. . . .Shares of Endocyte. . . fell 19.7% to $6.20 in after-hours trading yesterday, after the company announced that it has regained the worldwide rights to vintafolide in all indications from US pharma giant Merck & Co. . . .

. . .Merck, through a subsidiary, has decided that it will no longer pursue development of vintafolide. Just last month, Merck and Endocyte withdrew their European marketing approval application for the drug, after an independent monitoring board said that the PROCEED trial with vintafolide in combination with pegylated liposomal doxorubicin (PLD) versus PLD alone did not meet the pre-specified criteria for progression-free survival in patients with platinum-resistant ovarian cancer to allow continuation of the study. . . .


So it goes -- Merck will likely actually save some money from here onward, now that it has sent $120 million in upfronts to Endocyte. At least it won't continue to chase the rabbit down a hole.

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