UPDATED: 12.17.09 @ 8:40 AM EST -- Per Salmon's keen eye:
EM has 10% mortality.
It's also considered a mild form of more serious skin toxicities including Stevens Johnson Syndrome (SJS) and Toxic Epidermal Necrosis (TENS).
In SJS, mucus membranes are involved so you have burning in the vagina, mouth, urethra, eyelids etc.. SJS also has 10% mortality. Survivors often have scarring.
In TENS, sheets of skin die and slough off the body. Mortality is 40%.
December 17, 2009 8:05 AM
Significantly less alarming than the Remicade/Simponi warnings (see below), yet these new FDA warnings are likely to continue to add to the looming government-reimbursement tangles, and more general Vytorin/Zetia sales erosion, in the United States:
. . . .Vytorin® (ezetimibe/simvastatin) tablets
Detailed View: Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research (CDER) – November 2009
PATIENT PACKAGE INSERT
What are the possible side effects of Vytorin?
Raised red rash, sometimes with target-shaped lesions. . . .