Power Alley | It Is Likely That Mpox Immunity Only Lasts About Two Years -- After Either Infection, Or Vaccination: New Post Hoc Study, Of 90 Men...

This bit of news had long been suspected to be the case. And so, if you are a man who has sex with multiple other men (especially men who travel to or from Africa) -- you should consider getting booster vaccinations about every two years.

True enough, being infected (assuming you recover) will also give you about two years acquired immunity, but that seems. . . an unwise course, for personal health management (to say nothing of the risk you then present to your sexual partners).

In any event, here is the latest, from CIDRAP, at the U. of Minn.:

. . .The study, published today in The Journal of Infectious Diseases, followed up with 90 men—48 with prior mpox infection and 42 who received Jynneos vaccination—and measured mpox virus (MPXV)–specific neutralizing antibodies more than two years after infection or vaccination.

At the two-year mark, antibodies were frequently low or undetectable in both previously infected participants and vaccine recipients, though participants with prior infection were more likely than vaccine recipients to retain some detectable antibodies (33 of 48 [68.8%] vs 20/42 [47.6%]). . . . “This trend finds confirmation in real life practice in our open access sexual health clinic, where the majority of new infections are diagnosed in persons with no history of Mpox,” write the researchers. They also note that, “as already reported in literature and as observed in our daily experience,” most mpox cases in vaccinated individuals are self-limiting and low severity. . . .

Onward, grinning -- out, into the sunshine. Trump's tariffs are toast, next week. And hundreds of thousands of US businesses will file amended US federal tax returns, to claim dollar for dollar refunds for them. They were. . . taxes, afterall. Out.

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