tag:blogger.com,1999:blog-4241416962008169508.post4443905208610678124..comments2024-03-27T21:03:58.972-04:00Comments on Just A Life Sciences Blog...: The Ethics Of The Coming Head To Head Ebola Vaccine Candidates Trial: NYT's "Room For Debate"Unknownnoreply@blogger.comBlogger1125tag:blogger.com,1999:blog-4241416962008169508.post-52928270410742945332014-12-10T05:58:26.764-05:002014-12-10T05:58:26.764-05:00I am surprised that you are not getting any commen...I am surprised that you are not getting any comments to your posts.<br /><br />STEPPED WEDGE DESIGN for ebola vaccine field studies!!<br /><br />I have not heard all the arguments by the USG for pushing the Randomized controlled Trials (RCT).<br /><br />The FDA has recently published their reasoning for performing RCT for ebola therapeutics<br /><br />Cox, E., Borio, L., Temple, R., 2014. Evaluating Ebola Therapies - The Case for RCTs. N. Engl. J. Med. doi:10.1056/NEJMp1414145 <br /><br />and there were significant debates over the vaccine Phase 3 stuudy designs at the WHO ebola meeting at the end of September.<br /><br />This is quite the ethical quagmire.<br /><br />Birdmannoreply@blogger.com